Sf'nN

The abstract search whirley gig thingy is up for SfN, which means public disclosure, which means I can post info.

In case you're interested, two posters from our lab have been chosen for the SfN Press Book:
- (517.4/UU20) Directional tuning in motor cortex of a person with ALS (Simeral, Kim, ...)
- (517.15/VV1) Motor cortex local field potentials and multi-unit activity during intended movements in humans with tetraplegia (King, Truccolo, ...)

The lab has several great posters on display, so do a search for 'Donoghue' or 'Hochberg' for more. I'll post a list later with all the kids' posters linked.

Here's mine and Wilson's:

Program#/Poster#:	517.15/VV1
Title:	Motor cortex local field potentials and multi-unit activity during intended movements in humans with tetraplegia
Location:	San Diego Convention Center: Halls B-H
Presentation Start/End Time:	Monday, Nov 05, 2007, 3:00 PM - 4:00 PM
Authors:	*B. KING1, W. TRUCCOLO1, G. M. FRIEHS2,3, J. STEIN4, J. P. DONOGHUE1,5,6, L. R. HOCHBERG1,5,7; 1Dept. of Neurosci., 2Dept. of Clin. Neurosciences, Brown Univ., Providence, RI; 3Dept. of Neurosurgery, Rhode Island Hosp., Providence, RI; 4Dept. of Physical Med. and Rehabil., Spaulding Rehabil. Hospital, Harvard Med. Sch., Boston, MA; 5Rehabil. Res. and Develop. Service, Dept. of Veterans Affairs Med. Ctr., Providence, RI; 6Cyberkinetics Neurotechnology Systems, Inc., Foxborough, MA; 7Dept. of Neurology, Massachusetts Gen. Hospital, Brigham and Women’s Hospital, and Spaulding Rehabil. Hospital, Harvard Med. Sch., Boston, MA
We examined the relationships between motor cortex (MI) local field potentials (LFP) and multiunit activity (MUA) and intended movement in two humans with tetraplegia due to spinal cord transection (participant S1) or pontine stroke (S3). As part of a pilot clinical trial of the BrainGate Neural Interface System (IDE), a microelectrode array was chronically implanted in the dominant MI arm (knob) area in each participant. We investigated LFP and MUA activities offline in two main tasks: imagined pursuit tracking of a cursor moving on a computer monitor, and a 4 or 8-direction ‘neural cursor’ center-out step tracking task in which the cursor position was driven by the participant’s motor intention, decoded from MI spiking activity via a neural interface system. Recorded intra-cortical LFPs during the center-out task had features similar to those previously observed during reaching movements in monkeys. Typical attenuation of beta-oscillation (~20 Hz) and ‘motor’ event related potentials (ERPs) appeared 200-500ms after the instruction to move to the target. ERPs were statistically different (p<0.05)>
Disclosures:	B. King, None; W. Truccolo, None; G.M. Friehs, Cyberkinetics Neurotechnology Systems, Inc., B. Research Grant (principal investigator, collaborator or consultant and pending grants as well as grants already received); Cyberkinetics Neurotechnology Systems, Inc., E. Ownership Interest (stock, stock options, patent or other intellectual property); Cyberkinetics Neurotechnology Systems, Inc., F. Consultant/Advisory Board; J. Stein, None; J.P. Donoghue, Cyberkinetics Neurotechnology Systems, Inc., E. Ownership Interest (stock, stock options, patent or other intellectual property); Chief Scientific Officer: Cyberkinetics Neurotechnology Systems, Inc., Other; L.R. Hochberg, Cyberkinetics Neurotechnology Systems, Inc., B. Research Grant (principal investigator, collaborator or consultant and pending grants as well as grants already received).
Support:	Office of Research and Development, Rehabilitation Research and Development Service, Dept. of Veterans Affairs Medical Center, Providence, RI
	National Institute of Neurological Disorders and Stroke (NINDS) Neural Prosthesis Program, NINDS Grant NS25074
	Office of Naval Research (award N00014-06-1-0185)
	Cyberkinetics Neurotechnology Systems, Inc.